Outer hair cells isolation from postnatal Sprague–Dawley rats
نویسندگان
چکیده
منابع مشابه
Comparison of isolated outer hair cells from five mammalian species.
Live outer hair cells were isolated from guinea pig, chinchilla, rat, mouse, and gerbil. The organ of Corti from selected turns of the cochlea was briefly incubated with collagenase and outer hair cells were separated from the tissue by micromanipulation under microscopic observation. Morphological criteria for cell viability were: cylindrical cell shape without swelling or distortion of the me...
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Normal hearing in mammals depends on sound amplification by outer hair cells (OHCs) presumably by their somatic motility and force production. However, the role of OHC force production in cochlear amplification and frequency tuning are not yet fully understood. Currently, available OHC manipulation techniques for physiological or clinical studies are limited by their invasive nature, lack of pr...
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Mechanical amplification of acoustic signals is apparently a common feature of vertebrate auditory organs. In non-mammalian vertebrates amplification is produced by stereociliary processes, related to the mechanotransducer channel complex and probably to the phenomenon of fast adaptation. The extended frequency range of the mammalian cochlea has probably co-evolved with a novel hair cell type, ...
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6.1 The basics of wave propagation 6.1/a Effects of changes in standard parameters 6.2 Feedback between outer hair cells 6.2/a Feedback topology 6.2/b Response of three rows of cells 6.3 Modeling squirting wave excitation of the OHC array 6.3/a Explicit solution of the many-cell problem: full wavelength resonance Results and derivations 6.3/b Explicit solution of the many-cell problem: half-wav...
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We provide evidence from a newly established, conditionally immortal cell line (UB/UE-1) that vestibular supporting cells from the mammalian inner ear can differentiate postnatally into more than one variant of hair cell. A clonal supporting cell line was established from pure utricular sensory epithelia of H2k(b)tsA58 transgenic mice 2 d after birth. Cell proliferation was dependent on conditi...
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ژورنال
عنوان ژورنال: World Journal of Otorhinolaryngology - Head and Neck Surgery
سال: 2019
ISSN: 2095-8811
DOI: 10.1016/j.wjorl.2018.01.001